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Home >  Chemical Encyclopedia > Miscellaneous > Chemical Reagents > Halides > 1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS No.:

1496551-72-4

 Formula:

C10H13ClN2O5

 Molecular Weight: 276.67400
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Description

Chloro Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.

Basic Info

Chemical Name

 1-((2R,3R,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Synonyms

2-chloro-2′-C-methyl-uridine; 2'-chloro-2'-methyluridine;

CAS No.

 1496551-72-4

Molecular Formula

 C10H13ClN2O5

Molecular Weight

 276.67400

PSA

 104.55000

LogP

 -1.21530
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