1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Acute toxicity - Dermal, Category 4

Acute toxicity - Inhalation, Category 4

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H312 Harmful in contact with skin H332 Harmful if inhaled H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/…if you feel unwell. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Treatment is symptomatic and supportive. Oils should not be used as either cathartics or dermal cleansing agents, as they increase absorption. Gastric lavage and use of activated charcoal and sodium sulfate are indicated for ingestion. If dermal exposure occurred, contaminated clothes should be removed, and the skin should be thoroughly cleansed with soap and water. Management of seizures in both children and adults is with Valium or phenobarbital. Respiratory depression and even respiratory arrest especially with concomitant use of Valium and phenobarbital in children, may occur. These drugs preferably should be used only in critical care areas where emergency endotracheal intubation can be performed. ... Epinephrine can not be utilized in patients with organochlorine poisoning, as the organochlorines induce myocardial irritability and ventricular arrhythmias may occur. However, dopamine may be necessary in the event of hypotension unresponsive to fluid administration, and epinephrin may be necessary in the event of cardiopulmonary arrest. ... In a critically ill patient with unknown insecticide exposure, ... Atropine must be used with caution, as it can cause ventricular irritability, especially when a myocardial irritant such as an organochlorine is present. ... Hematologic, hepatic (especially with endrin, which is markedly hepatotoxic), and renal studies as well as cardiopulmonary monitoring should be carried out in acute intoxication from lindane or other organochlorines for at least 48 to 72 hr. Long term hematologic follow-up is necessary for the patient with lindane intoxication. As the carrier for these agents may be xylene or a petroleum distillate, management also must include observation and treatment for these entities. /Organochlorine pesticides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Keep in well-ventilated area.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

NONVOLATILE

10.3 Possibility of hazardous reactions

NonflammableMETHOXONE SODIUM SALT is a salt of a chlorinated benzoic acid.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Reacts with alkalis to form salts

10.6 Hazardous decomposition products

When heated to decomposition it emits toxic fumes of /hydrogen chloride and nitrogen oxides/.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat male oral 700 mg/kg
• Inhalation: no data available
• Dermal: LD50 Rat percutaneous >1000 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Not Likely to be Carcinogenic to Humans

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50 Salmo gairdneri (Rainbow trout) 232 mg/l/96 hr /Conditions of bioassay not specified
• Toxicity to daphnia and other aquatic invertebrates: no data available
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Microbial degradation of MCPA in soil was followed by measuring radiolabeled 14-CO2 evolution(1); in non-acclimated soil, CO2 evolution reached 40-50% after 78 days of incubation(1). At an initial MCPA concn of 5 mg/kg, CO2 evolution increased markedly after a 2-3 week lag period indicating that microbial adaptation will increase the degradation rate(1); optimum degradation occurred in soil with a moisture content of 0.6 to 1.2 field capacity(1) while degradation in dry soil was negligible(1). The importance of acclimation was demonstrated in soil degradation tests in which degradation in unacclimated soil required 46-82 days, but only 5-14.5 days were required for a subsequent degradation in the same soil(2); sterilization tests (via sodium azide) indicated that all soil degradation was microbial in nature(2). The results of laboratory studies indicated that 14C-labeled MCPA would degrade faster in soils that had received previous applications than in untreated soils(3). Microbial degradation in soil is probably due to hydroxylation with cleavage of the ether linkage (4). The dechlorination of MCPA was indicated as an acid-yielding reaction and was observed to reduce the pH in a mixed culture medium; no degradation occurred in cultures above pH 8.5 and degradation was slower at higher concns(5). In samples of sandy clay soil (pH 5.2, organic matter 6.3%) at field capacity moisture content (18.2%) and incubated at 23°C for up to 32 weeks, MCPA, at initial concns of 10, 100, 200 and 500 ppm, degraded more rapidly at the lower concns(6). Respective losses of 40%, 60% and 90% were observed at 2, 8 and 32 weeks; the degradates were identified as 4-chloro-o-cresol, 5-chloro-3-methylcatechol, and 2,6-dimethoxyphenol(6).

12.3 Bioaccumulative potential

A BCF of 1 was determined for trout at MCPA aqueous concns of 10-100 mg/l and using an exposure period of 10-28 day(1). In a model aquatic ecosystem study, BCFs of <1 were measured in fish and snails for the sodium salt of 2-methyl-4-chlorophenoxyacetic acid(2,3). According to a classification scheme(3), these BCF values suggest the potential for bioconcentration in aquatic organisms is low. MCPA is absorbed through leaves or roots and is readily translocated in plants(4).

12.4 Mobility in soil

MCPA adsorption coefficients (Kd) of 0.7 to 1.0 were measured in three soils (loamy sand and sandy loam types)(1); based upon humus contents of 2.4-3.0%(1),the Koc values of the three soils are approximately 60, 52 and 50, respectively. A similar Kd value of 0.4 was observed in a garden soil(2). Using soil thin-layer chromatography, Rf values of 0.6-1.0 were measured for Chillum silt loam (3.1% organic matter), Lakeland sand loam (0.9% organic matter) and Hagerstown silty clay loam (1.4% organic matter)(3,4); these Rf values classify MCPA as mobile in soil(3,4). When MCPA was applied to a rice field, an observed 70% decrease in MCPA was attributed to losses through soil percolation(5). In a laboratory study of leaching columns with either turf grass soil or two subsoils, most of the applied MCPA (95.4-99.0%) eluted with the first 100-ml fraction of leaching water applied to the columns, indicating that MCPA did not bind to the soils(6). According to a classification scheme(7), these Koc values suggest that MCPA is expected to have high mobility in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.